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Amyotrophic Lateral Sclerosis Mechanism: Insights from the Caenorhabditis elegans Models

3 Jan 2024

Abstract excerpt

Amyotrophic Lateral Sclerosis (ALS) is a debilitating neurodegenerative condition characterized by the progressive degeneration of motor neurons. Despite extensive research in various model animals, the cellular signal mechanisms of ALS remain elusive, impeding the development of efficacious treatments. Among these models, a well-characterized and diminutive organism, Caenorhabditis elegans (C. elegans), has...

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PMID: 38201303
DOI: 10.3390/cells13010099

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