Article

“Stick-slip dynamics of cell adhesion triggers spontaneous symmetry breaking and directional migration”

2018-06-25

Abstract excerpt

Directional cell motility during organism and tissue development, homeostasis and disease requires symmetry breaking. This process relies on the ability of single cells to establish a front-rear polarity, and can occur in absence of external cues. The initiation of migration has been attributed to the spontaneous polarization of cytoskeleton components, while the spatiotemporal evolution of cytoskeletal forces ari...

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Identifiers and source

Literature Corpus work: 66c433ea-bac1-50ca-8aed-14da711501ea
DOI: 10.1101/354696

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