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Article

Lamellipodia nucleation by filopodia depends on integrin occupancy and downstream Rac1 signaling.

Experimental cell research - 1 Feb 2008

Guillou Hervé, Depraz-Depland Adeline, Planus Emmanuelle, Vianay Benoit, Chaussy Jacques, Grichine Alexei, Albigès-Rizo Corinne, Block Marc R

Abstract excerpt

Time-lapse video-microscopy unambiguously shows that fibroblast filopodia are the scaffold of lamellipodia nucleation that allows anisotropic cell spreading. This process was dissected into elementary stages by monitoring cell adhesion on micropatterned extracellular matrix arrays of various pitc...

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Source

Identifiers

PMID: 18067889
DOI: 10.1016/j.yexcr.2007.10.026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18067889-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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