Article

Surprising regulatory plasticity for the conserved HOG pathway in diverse <i>Saccharomyces cerevisiae</i> strains

2025-12-28

Abstract excerpt

Mitogen-activated protein kinases (MAPKs) display remarkable regulatory plasticity across evolution, ranging from highly specialized pathways to broadly responsive global signaling hubs. In the budding yeast Saccharomyces cerevisiae , the high-osmolarity glycerol (HOG) network has served as a paradigm for largely stress-specific MAPK signaling, where the Hog1 MAPK coordinates osmoadaptation. This stands in sharp...

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Literature Corpus work: 66b08409-d18e-5727-8e6d-88b1b4a5bbf0
DOI: 10.64898/2025.12.28.696518

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