Article
Cdc37p is involved in osmoadaptation and controls high osmolarity-induced cross-talk via the MAP kinase Kss1p.
FEMS yeast research - 1 Sept 2007
Yang Xiao-Xian, Hawle Patricija, Bebelman Jan Paul, Meenhuis Annemarie, Siderius Marco, van der Vies Saskia M
Abstract excerpt
Cdc37p, the p50 homolog of Saccharomyces cerevisiae, is an Hsp90 cochaperone involved in the targeting of protein kinases to Hsp90. Here we report a role for Cdc37p in osmoadaptive signalling in this yeast. The osmosensitive phenotype that is displayed by the cdc37-34 mutant strain appears not to...
Topics
- Adaptation, Physiological
- Cell Cycle Proteins
- Cell Wall
- Gene Expression Regulation, Fungal
- Glycerol
- HSP90 Heat-Shock Proteins
- Mitogen-Activated Protein Kinases
- Molecular Chaperones
- Mutation
- Osmotic Pressure
- Phenotype