Influence of <i>APOA5</i> locus on the treatment efficacy of three statins: evidence from a randomized pilot study in Chinese subjects

Abstract excerpt

Pharmacogenetics or pharmacogenomics approaches are important for addressing the individual variabilities of drug efficacy especially in the era of precision medicine. One particular interesting gene to investigate is APOA5 which has been repeatedly linked with the inter-individual variations of serum triglycerides. Here, we explored APOA5 -statin interactions in 195 Chinese subjects randomized to rosuvastatin (...

Topics

Open a Topic to create a Post that cites this publication.

• Apolipoprotein A-V
• Apolipoproteins A
• Diabetes Complications
• Endpoint Determination
• Hydroxymethylglutaryl-CoA Reductase Inhibitors
• Metabolic Syndrome
• Polymorphism, Single Nucleotide
• Triglycerides

Identifiers and source

Literature Corpus work

6697b24c-97ab-5142-ae61-f80019e8502a

DOI

10.1101/213629