Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of apolipoprotein A5 variants on statin treatment efficacy.

Pharmacogenomics - 1 Jun 2009

Hubacek Jaroslav A, Adamkova Vera, Prusikova Martina, Snejdrlova Michaela, Hirschfeldova Katerina, Lanska Vera, Ceska Richard, Vrablik Michal

Abstract excerpt

AIMS: Despite the fact that statin treatment efficacy is very high, there are substantial differences in treatment effectiveness among individuals. It is supposed that genetic predisposition plays an important role in these differences, but the contribution of individual polymorphisms is poorly understood. So far, more than 30 genes have been examined with ambiguous results. Apolipoprotein A5 is an important...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein A-V
Share to Apolipoproteins A

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholesterol, LDL

Share to Czech Republic

Share to Dyslipidemias

Share to Forecasting

Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

Share to Triglycerides

Source

Identifiers

PMID: 19530961
DOI: 10.2217/pgs.09.17

Genes

APOA5
APOE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of apolipoprotein A5 variants on statin treatment efficacy.PMID 19530961Read ↗

CYP3A4*1B and CYP3A5*3 SNPs significantly impact the response of Egyptian candidates to high-intensity statin therapy to atorvastatin.Semantic proximity Read ↗

Influence of 6 genetic variants on the efficacy of statins in patients with dyslipidemia.Semantic proximity Read ↗

Influence of <i>APOA5</i> locus on the treatment efficacy of three statins: evidence from a randomized pilot study in Chinese subjectsSemantic proximity Read ↗

Genetic contribution to lipid target achievement with statin therapy: a prospective study.Semantic proximity Read ↗

Impact of variants within seven candidate genes on statin treatment efficacy.Semantic proximity Read ↗

APOE genotype and the effect of statins on lipid outcomes: A meta-analysis.Semantic proximity Read ↗

An association study of 43 SNPs in 16 candidate genes with atorvastatin response.Semantic proximity Read ↗

Associations between four polymorphisms of the SLCO1B1 and effectiveness of the statins: a meta-analysis.Semantic proximity Read ↗

Statins personalized.Semantic proximity Read ↗

Function-impairing polymorphisms of the hepatic uptake transporter SLCO1B1 modify the therapeutic efficacy of statins in a population-based cohort.Semantic proximity Read ↗

APOE genotype and the effect of statins: a systematic review and meta-analysisSemantic proximity Read ↗

Lipid-lowering response to statins is affected by CYP3A5 polymorphism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.