Article

Age- and airway disease related gene expression patterns of key SARS-CoV-2 entry factors in human nasal epithelia

2021-05-25

Abstract excerpt

The global COVID-19 pandemic caused by SARS-CoV-2 predominantly affects the elderly. Differential expression of SARS-CoV-2 entry genes may underlie the variable susceptibility in different patient groups. Here, we examined the gene expression of key SARS-CoV-2 entry factors in mucosal biopsies to delineate the roles of age and existing chronic airway disease. A significant inverse correlation between ACE2 and age...

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Literature Corpus work: 92780d26-dfcb-5b38-a70b-44e938d3deeb
DOI: 10.1101/2021.05.23.21257673

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