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Lgr5 in cancer biology: functional identification of Lgr5 in cancer progression and potential opportunities for novel therapy

29 Jul 2019

Abstract excerpt

Cancer remains one of the leading lethal diseases worldwide. Identifying biomarkers of cancers might provide insights into the strategies for the development of novel targeted anti-cancer therapies. Leucine-rich repeat-containing G protein-coupled receptor 5 (Lgr5) has been recently discovered as a candidate marker of cancer stem cell populations. Aberrant increased expression of Lgr5 may represent one of the...

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PMID: 31358061
DOI: 10.1186/s13287-019-1288-8

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