Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cellular Expression, Trafficking, and Function of Two Isoforms of Human ULBP5/RAET1G

17 Feb 2009

Abstract excerpt

BACKGROUND: The activating immunoreceptor NKG2D is expressed on Natural Killer (NK) cells and subsets of T cells. NKG2D contributes to anti-tumour and anti-viral immune responses in vitro and in vivo. The ligands for NKG2D in humans are diverse proteins of the MIC and ULBP/RAET families that are upregulated on the surface of virally infected cells and tumours. Two splicing variants of ULBP5/RAET1G have been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Cell Function and Interaction
Share to Lymphoma Diagnosis and Treatment
Share to Platelet Disorders and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19223974
DOI: 10.1371/journal.pone.0004503

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cellular Expression, Trafficking, and Function of Two Isoforms of Human ULBP5/RAET1GPMID 19223974Read ↗

ULBP6/RAET1L is an additional human NKG2D ligandSemantic proximity Read ↗

Characterisation of RAET1E/ULBP4 exon 4 and 3' untranslated region genetic architecture reveals further diversity and allelic polymorphism.Semantic proximity Read ↗

NKG2D Receptor and Its Ligands in Host DefenseSemantic proximity Read ↗

Human NKG2D-ligands: cell biology strategies to ensure immune recognitionSemantic proximity Read ↗

NKG2D and MICA/B shedding: a ‘tag game’ between NK cells and malignant cellsSemantic proximity Read ↗

LGR5 targeting molecules as therapeutic agents for multiple cancer typesSemantic proximity Read ↗

Genetics, genomics, and evolutionary biology of NKG2D ligands.Semantic proximity Read ↗

LAIR1, an ITIM-Containing Receptor Involved in Immune Disorders and in Hematological NeoplasmsSemantic proximity Read ↗

A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cellsSemantic proximity Read ↗

NKG2D-ligands: Putting everything under the same umbrella can be misleading.Semantic proximity Read ↗

A Truncated Human NKG2D Splice Isoform Negatively Regulates NKG2D-Mediated FunctionSemantic proximity Read ↗

NKG2D signaling in cancer immunosurveillanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.