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Evolutionary epidemiology of <i>Streptococcus iniae</i> : linking mutation rate dynamics with adaptation to novel immunological landscapes

2018-06-25

Abstract excerpt

Pathogens continuously adapt to changing host environments where variation in their virulence and antigenicity is critical to their long-term evolutionary success. The emergence of novel variants is accelerated in microbial mutator strains (mutators) deficient in DNA repair genes, most often from mismatch repair and oxidised-guanine repair systems (MMR and OG respectively). Bacterial MMR/OG mutants are abundant in...

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Literature Corpus work
66477a8b-c380-512a-8d39-60cf9a810740
DOI
10.1101/355412
Open publication

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Evolutionary epidemiology of <i>Streptococcus iniae</i> : linking mutation rate dynamics with adaptation to novel immunological landscapesDOI 10.1101/355412
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