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Article

Mechanisms and impact of genetic recombination in the evolution of <i>Streptococcus pneumoniae</i>

1 Jan 2015

Abstract excerpt

Streptococcus pneumoniae (the pneumococcus) is a highly recombinogenic bacterium responsible for a high burden of human disease globally. Genetic recombination, a process in which exogenous DNA is acquired and incorporated into its genome, is a key evolutionary mechanism employed by the pneumococcus to rapidly adapt to selective pressures. The rate at which the pneumococcus acquires genetic variation through...

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PMID: 25904996
DOI: 10.1016/j.csbj.2015.03.007

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