Article
Evolutionary and population genomics of the cavity causing bacteria Streptococcus mutans.
Molecular biology and evolution - 1 Apr 2013
Cornejo Omar E, Lefébure Tristan, Bitar Paulina D Pavinski, Lang Ping, Richards Vincent P, Eilertson Kirsten, Do Thuy, Beighton David, Zeng Lin, Ahn Sang-Joon, Burne Robert A, Siepel Adam, Bustamante Carlos D, Stanhope Michael J
Abstract excerpt
Streptococcus mutans is widely recognized as one of the key etiological agents of human dental caries. Despite its role in this important disease, our present knowledge of gene content variability across the species and its relationship to adaptation is minimal. Estimates of its demographic history are not available. In this study, we generated genome sequences of 57 S. mutans isolates, as well as representative...
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