Article

The ERK5 MAP kinase regulates annexin complexes and membrane dynamics in embryonic stem cells

2024-07-03

Abstract excerpt

<h4>Summary</h4> The ERK5 MAP kinase signalling pathway controls key processes in mouse Embryonic Stem Cells (mESCs) maintenance, including expression of naïve pluripotency genes and a transcriptional programme for stem cell rejuvenation. However, quantitative proteomics suggests that ERK5 signalling controls levels of proteins implicated in diverse biological processes. Here, we show that Annexin A2 (ANXA2) and...

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Literature Corpus work: 6613e200-2278-5322-aa44-8024d547b121
DOI: 10.1101/2024.07.03.598211

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