Back to search

Article

Versatile roles of Annexin A4 in ccRCC: impact on membrane repair, transcriptional signatures, and composition of the tumor microenvironment

2024-06-03

Abstract excerpt

Clear cell renal cell carcinoma (ccRCC) is the most prevalent type of renal malignant disease and is characterized by dismal prognosis in the metastasized setting. Invasive growth of cancer cells relates to high levels of compressive forces translating to relevant damage of the plasma membrane. However, functional implications of protein machineries required for plasma membrane repair in ccRCC are not yet complete...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
88b9b4c8-aede-594c-ba80-c0fe3a527b38
DOI
10.1101/2024.05.31.596161
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Versatile roles of Annexin A4 in ccRCC: impact on membrane repair, transcriptional signatures, and composition of the tumor microenvironmentDOI 10.1101/2024.05.31.596161
Potential prognostic and therapeutic value of ANXA8 in renal cell carcinoma: based on the comprehensive analysis of annexins familySemantic proximity
Deep visual multi-omics profiling reveals mechanisms that underlie cancer cell differentiation and aggressiveness in clear cell renal cell carcinomaSemantic proximity
A spatially anchored transcriptomic atlas of the human kidney papilla identifies significant immune injury in patients with stone diseaseSemantic proximity
Evaluation of Annexins Family as Potential Biomarker for Predicting Progression and Prognosis in Clear Renal Cell CarcinomaSemantic proximity
Proteomic characterization of sporadic clear cell renal cell carcinoma reveals a matrix-dense pseudocapsule and heterogeneous tumor subtypesSemantic proximity
Loss of BAP1 Results in Growth Inhibition and Enhances Mesenchymal–Epithelial Transition in Kidney Tumor CellsSemantic proximity
High Cytoplasmic and Membranous Versus Nuclear Talin-1 Expression Associated With Malignancy Potential and Poor Survival in Clear Cell Renal Cell CarcinomaSemantic proximity
Low-branching vessel architecture shapes immune cell niches and predicts immune responses in renal cancerSemantic proximity
RUNX1 Is a Driver of Renal Cell Carcinoma Correlating with Clinical OutcomeSemantic proximity
Increased spatial coupling of integrin and collagen IV in the immunoresistant clear cell renal cell carcinoma tumor microenvironmentSemantic proximity
Complement activation shapes immune contexture and immunotherapy response in clear cell renal cell carcinomaSemantic proximity
Identification and Functional Characterization of pVHL-Dependent Cell Surface Proteins in Renal Cell CarcinomaSemantic proximity
Select a neighboring publication to make it the new centre.