Article

Predicting the prevalence of complex genetic diseases from individual genotype profiles using capsule networks

2023-02-13

Abstract excerpt

Abstract Diseases that have a complex genetic architecture tend to suffer from considerable amounts of genetic variants that, although playing a role in the disease, have not yet been revealed as such. Two major causes for this phenomenon are genetic variants that do not stack up effects, but interact in complex ways; in addition, as recently suggested, the omnigenic model postulates that variants interact in a ho...

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Literature Corpus work: 65fd2efb-246b-5cae-9a5f-6dea5e7d29f3
DOI: 10.1038/s42256-022-00604-2

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