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Article

Using machine learning to predict and analyze complex trait diseases: Lessons from a simple abstract model.

PloS one - 1 Jan 2026

Maimon Eden, Bondi Ori, Moult John, Unger Ron

Abstract excerpt

The ability to predict individual genetic susceptibility to a complex trait disease is a major challenge in modern medicine. One approach to addressing this challenge utilizes an additive combination of contributions from a large number of single nucleotide polymorphisms (SNPs), with weights derived from Genome Wide Association Studies (GWAS). While this approach is somewhat successful in predicting whether an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41729933
DOI: 10.1371/journal.pone.0342490
PMCID: PMC12928469

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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