Article

Kv1.1 channel dysfunction in parvalbumin-positive interneurons contributes to anxiety-like behaviors in young adult presenilin 1/2 conditional double knockout mice

2023-08-02

Abstract excerpt

<title>Abstract</title> <p>Anxiety, as an early manifestation of Alzheimer’s disease (AD), plays a significant role in the initial stages of cognitive decline and has a negative impact on the progression of the disease. However, the specific pathological mechanisms underlying anxiety in early stage of AD remain largely unknown. In this study, we investigated anxiety-like behaviors in presenilin 1/2 conditional do...

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Literature Corpus work: 65f39b36-8366-54b0-a662-1f6161541189
DOI: 10.21203/rs.3.rs-3201565/v1

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Kv1.1 channel dysfunction in parvalbumin-positive interneurons contributes to anxiety-like behaviors in young adult presenilin 1/2 conditional double knockout miceDOI 10.21203/rs.3.rs-3201565/v1Read

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