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α5-GABAA receptor modulation reverses behavioral and neurophysiological correlates of psychosis in rats with ventral hippocampal Alzheimer’s Disease-like pathology

2023-05-23

Abstract excerpt

<title>Abstract</title> <p>Of the 35 million people in the world who suffer with Alzheimer’s Disease (AD), up to half also experience comorbid psychosis (delusions and hallucinations). Antipsychotics, used to treat symptoms of psychosis, are contraindicated in elderly patient populations because they increase the risk of premature death. The hippocampus is a region of the brain that has been reported to be hypera...

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Literature Corpus work
60cf754d-1c05-5df6-a953-17f4d8eadf84
DOI
10.21203/rs.3.rs-2809328/v1
Open publication

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α5-GABAA receptor modulation reverses behavioral and neurophysiological correlates of psychosis in rats with ventral hippocampal Alzheimer’s Disease-like pathologyDOI 10.21203/rs.3.rs-2809328/v1
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