Article

Estimation of the allelic status of apolipoprotein E4 isoforms with fully automated LUMIPULSE® assays

2023-10-16

Abstract excerpt

Aim: Apolipoprotein E (ApoE) isoforms, especially the ApoE4 isoform, are genetic risk factors for Alzheimer’s disease (AD). Moreover, the APOE ε4 haplotype has a dose-dependent association with an increased risk of amyloid-related imaging abnormalities (ARIA) in individuals receiving disease-modifying therapy for AD. Therefore, the importance of APOE genotyping or proteotyping has been highlighted. Here, the autho...

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Literature Corpus work: 65d31000-2192-54d1-a478-356fdd38dccc
DOI: 10.37349/en.2023.00024

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