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Article

Apolipoprotein E proteotyping as a valid alternative to genotyping in clinical practice.

Journal of Alzheimer's disease : JAD - 1 Jun 2026

Alcalá Ramírez Del Puerto José Manuel, Ortega-Madueño Isabel, Gil-Moreno María José, Abizanda-Saro Pablo, Palacios-Sarmiento Marta, Millán-Guirado Rafael, Cruz-Cárdenas María, Matías-Guiu Jordi A

Abstract excerpt

The apolipoprotein E ε4 allele (APOE ε4) is associated with higher incidence of amyloid-related imaging abnormalities in patients with Alzheimer's disease undergoing anti-amyloid therapy, underscoring the importance of allele status testing. In this study, plasma ApoE4 levels were measured in 70 participants using Lumipulse®G Pan-ApoE and ApoE4 assays and compared with traditional genotyping. ApoE4 concentrations...

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Identifiers

PMID: 41940854
DOI: 10.1177/13872877261438522

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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