Article

Aging affects K <sub>V</sub> 7 channels and perivascular-adipose tissue-mediated vascular tone

2021-04-11

Abstract excerpt

Aging is an independent risk factor for hypertension, cardiovascular morbidity, and mortality. However, detailed mechanisms linking aging to cardiovascular disease are unclear. We studied the aging effects on the role of perivascular adipose tissue and downstream vasoconstriction targets, voltage-dependent K V 7 channels, and their pharmacological modulators (flupirtine, retigabine, QO58, QO58-lysine) in a murine...

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Literature Corpus work: 65cdfc86-cc89-5646-8695-b699cf3b3444
DOI: 10.1101/2021.04.11.438975

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