Article

LeGO-Teknik reveals that the neurogenesis pathway is a clone-specific hallmark of brain metastasis in breast cancer

2025-07-27

Abstract excerpt

Breast cancer exhibits substantial inter- and intra-patient heterogeneity. Yet the molecular features underlying this diversity and their roles in tumour progression are not yet fully elucidated. Within a primary tumour, certain clones possess a unique capacity to metastasize to distant organs, such as the brain, and this propensity may be associated with specific gene expression profiles. To investigate this phen...

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Literature Corpus work: 65ae4ea5-bdf5-5d76-8887-608bf659abc7
DOI: 10.1101/2025.07.23.666035

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