Article

Deep analysis of the Major Histocompatibility Complex associations using covariate analysis and haploblocks unravels new mechanisms for the molecular etiology of Elite Control in AIDS

2024-12-10

Abstract excerpt

<h4>Introduction</h4> We have reanalyzed the genomic data from the International Collaboration for the Genomics of HIV (ICGH), focusing on HIV-1 Elite Controllers (EC). <h4>Methods</h4> A genome-wide association study (GWAS) was performed, comparing 543 HIV-1 EC individuals with 3,272 uninfected controls (CTR) of European ancestry. 8 million single nucleotide polymorphisms (SNPs) and HLA class I and class II gen...

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Literature Corpus work: 6597b5ff-7be7-5d84-acdc-0fed5b309bf0
DOI: 10.1101/2024.12.07.625684

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