Article
Genome-Wide Association Studies of HIV-1 Host Control in Ethnically Diverse Chinese Populations.
Scientific reports - 3 Jun 2015
Wei Zejun, Liu Yang, Xu Heng, Tang Kun, Wu Hao, Lu Lin, Wang Zhe, Chen Zhengjie, Xu Junjie, Zhu Yufei, Hu Landian, Shang Hong, Zhao Guoping, Kong Xiangyin
Abstract excerpt
Genome-wide association studies (GWASs) have revealed several genetic loci associated with HIV-1 outcome following infection (e.g., HLA-C at 6p21.33) in multi-ethnic populations with genetic heterogeneity and racial/ethnic differences among Caucasians, African-Americans, and Hispanics. To systematically investigate the inherited predisposition to modulate HIV-1 infection in Chinese populations, we performed GWASs...
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