Article
Evidence after imputation for a role of MICA variants in nonprogression and elite control of HIV type 1 infection.
The Journal of infectious diseases - 15 Dec 2014
Le Clerc Sigrid, Delaneau Olivier, Coulonges Cédric, Spadoni Jean-Louis, Labib Taoufik, Laville Vincent, Ulveling Damien, Noirel Josselin, Montes Matthieu, Schächter François, Caillat-Zucman Sophie, Zagury Jean-François
Abstract excerpt
Past genome-wide association studies (GWAS) involving individuals with AIDS have mainly identified associations in the HLA region. Using the latest software, we imputed 7 million single-nucleotide polymorphisms (SNPs)/indels of the 1000 Genomes Project from the GWAS-determined genotypes of individuals in the Genomics of Resistance to Immunodeficiency Virus AIDS nonprogression cohort and compared them with those...
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