Article

Two-module architecture of ribosome-associated quality control in human brain: divergent co-expression networks of PELO, LTN1, and NEMF

2026-02-26

Abstract excerpt

<title>Abstract</title> <p> Background Ribosome-associated quality control (RQC) resolves stalled translational complexes through sequential ribosome rescue (PELO), nascent chain ubiquitination (LTN1), and C-terminal alanine–threonine tail modification (NEMF). While the biochemical sequence of these events is well characterized, the broader transcriptional coordination of individual RQC components with other ce...

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Literature Corpus work: cd95afe6-7dc0-57c5-b58f-03cbf8c86827
DOI: 10.21203/rs.3.rs-8887367/v1

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