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Single-Cell Deconvolution of Head and Neck Squamous Cell Carcinoma

11 Mar 2021

Abstract excerpt

Complexities in cell-type composition have rightfully led to skepticism and caution in the interpretation of bulk transcriptomic analyses. Recent studies have shown that deconvolution algorithms can be utilized to computationally estimate cell-type proportions from the gene expression data of bulk blood samples, but their performance when applied to tumor tissues, including those from head and neck, remains...

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PMID: 33799782
DOI: 10.3390/cancers13061230

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