Article

Exon-skipping antisense oligonucleotides targeting SUMO1 and SUMO2 demonstrate chemosensitizing effects in NSCLC cells in tissue culture

2026-05-05

Abstract excerpt

<title>Abstract</title> <p>Lung cancer remains a leading cause of cancer-related death, highlighting the urgent need for new treatment strategies. SUMOylation, a post-translational modification that regulates DNA repair, replication, and cell cycle progression, is often increased in cancers and is a promising therapeutic target. Previously, we identified alternative splicing events affecting the SUMO transcripts,...

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Literature Corpus work: 65697950-35aa-53a6-bf57-d8e07f51f96f
DOI: 10.21203/rs.3.rs-9361591/v1

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Exon-skipping antisense oligonucleotides targeting SUMO1 and SUMO2 demonstrate chemosensitizing effects in NSCLC cells in tissue cultureDOI 10.21203/rs.3.rs-9361591/v1Read

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