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SARS-CoV-2 nsp16 is regulated by host E3 ubiquitin ligases, UBR5 and MARCHF7

2024-08-30

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), remains a global public health threat with considerable economic consequences. The non-structural protein 16 (nsp16), in complex with nsp10, facilitates the final viral mRNA capping step through its 2′-O-methylase activity, helping the virus to evade host immunity and prevent mRNA degradation....

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Literature Corpus work
652c6387-0b9c-544c-bc7e-bfc884840eeb
DOI
10.1101/2024.08.30.610469
Open publication

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SARS-CoV-2 nsp16 is regulated by host E3 ubiquitin ligases, UBR5 and MARCHF7DOI 10.1101/2024.08.30.610469
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