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SARS-CoV-2 non-structural protein 13 (nsp13) hijacks host deubiquitinase USP13 and counteracts host antiviral immune response

11 Mar 2021

Abstract excerpt

COVID-19 (Coronavirus Disease-2019), a respiratory disease caused by the novel virus strain, SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), an enveloped, positive-sense, single-stranded RNA betacoronavirus of the family Coronaviridae , has spread worldwide. 1 Notably, SARS-CoV-2 infection led to poor induction of type I interferon response, and the impaired type I IFN responses have been shown to...

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PMID: 33707416
DOI: 10.1038/s41392-021-00509-3

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