Article

Enhanced production of recombinant nattokinase in Bacillus subtilis by promoter optimization

2011-01-01

Abstract excerpt

Nattokinase (NK) is a health product for the prevention and potential control of thrombosis diseases. To explore the possibility of enhancing NK production in Bacillus subtilis by altering the promoter of NK gene (PaprN), we tested several methods. We substituted the wild-type â10 box (TACAAT) of PaprN with the consensus sequence (TATAAT) of ÏA-dependent promoters, mutated the original â35 box (TACTAA) to a p...

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Identifiers and source

Literature Corpus work: 652a8b9c-1ebc-5521-9e57-def05b5a42ae
DOI: 10.1007/s11274-010-0432-5

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