Article

Modeling Friedreich’s ataxia with Bergmann glia-enriched human cerebellar organoids

2025-05-16

Abstract excerpt

The human cerebellum is a specialized brain region that is involved in various neurological and psychiatric diseases but has been challenging to study in vitro due its complex neurodevelopment and cellular diversity. Despite the progress in generating neural tissues from human induced pluripotent stem cells (iPSCs), an organoid model that recapitulates the key features of cerebellar development has not been widel...

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Literature Corpus work: 64c345dc-8d61-59cf-9e3d-724ddeaebea3
DOI: 10.1101/2025.05.16.654315

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