Article

Untangling mechanisms for cerebellar neural specification using human pluripotent stem cell-derived organoids

2026-04-29

Abstract excerpt

The cerebellum is one of the most complex structures of the brain composed of a high diversity of GABAergic and glutamatergic neurons. Whereas cerebellar biogenesis has been extensively studied in the mouse, an in-depth characterization of genes and pathways involved in cerebellar specification and maturation in the humans remains overlooked. Here, we used human pluripotent stem cells (hPSC)-derived cerebellar org...

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Literature Corpus work: 1bdfa653-49ff-5bb0-94d2-4caa18b145d4
DOI: 10.64898/2026.04.27.720597

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