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Transcriptome profiling of human pluripotent stem cell-derived cerebellar organoids reveals faster commitment under dynamic conditions

2021-01-27

Abstract excerpt

Human induced pluripotent stem cells (iPSCs) have great potential for disease modeling. However, generating iPSC-derived models to study brain diseases remains a challenge. In particular, the ability to recapitulate cerebellar development in vitro is still limited. We presented a reproducible and scalable production of cerebellar organoids by using the novel Vertical-Wheel single-use bioreactors, in which functio...

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Literature Corpus work
e8628c05-d2df-54af-9f56-fc7457641f70
DOI
10.1101/2021.01.27.428468
Open publication

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Transcriptome profiling of human pluripotent stem cell-derived cerebellar organoids reveals faster commitment under dynamic conditionsDOI 10.1101/2021.01.27.428468
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