Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Simplified Method for Generating Purkinje Cells from Human-Induced Pluripotent Stem Cells

3 Feb 2018

Abstract excerpt

The establishment of a reliable model for the study of Purkinje cells in vitro is of particular importance, given their central role in cerebellar function and pathology. Recent advances in induced pluripotent stem cell (iPSC) technology offer the opportunity to generate multiple neuronal subtypes for study in vitro. However, to date, only a handful of studies have generated Purkinje cells from human pluripotent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomedical Ethics and Regulation
Share to CRISPR and Genetic Engineering
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29397531
DOI: 10.1007/s12311-017-0913-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Simplified Method for Generating Purkinje Cells from Human-Induced Pluripotent Stem CellsPMID 29397531Read ↗

Altered temporal sequence of transcriptional regulators in the generation of human cerebellar granule cellsSemantic proximity Read ↗

Modeling Friedreich’s ataxia with Bergmann glia-enriched human cerebellar organoidsSemantic proximity Read ↗

Scalable Generation of Mature Cerebellar Organoids from Human Pluripotent Stem Cells and Characterization by ImmunostainingSemantic proximity Read ↗

Untangling mechanisms for cerebellar neural specification using human pluripotent stem cell-derived organoidsSemantic proximity Read ↗

Process-based expansion and neural differentiation of human pluripotent stem cells for transplantation and disease modelingSemantic proximity Read ↗

Single-cell sequencing of human iPSC-derived cerebellar organoids shows recapitulation of cerebellar developmentSemantic proximity Read ↗

Novel fragile X syndrome 2D and 3D brain models based on human isogenic FMRP-KO iPSCsSemantic proximity Read ↗

A human iPS cell line for ready-to-use human iAstrocytes that support human neuronsSemantic proximity Read ↗

Complementary 2D and 3D cultures deriving from a single human cortical differentiation process recapitulate in vitro neurodevelopmental and neurogenerative features of juvenile Huntington’s DiseaseSemantic proximity Read ↗

Novel genetic features of human and mouse Purkinje cell differentiation defined by comparative transcriptomicsSemantic proximity Read ↗

Generation of human haploid neural stem cells from parthenogenetic embryonic stem cellsSemantic proximity Read ↗

Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.