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Zika virus-induced fetal demise is driven by strain- and dose-specific RLR-driven activation of the interferon response in the decidua, placenta, and fetus in <i> Ifnar1 <sup>-/-</sup> </i> mice

2025-02-13

Abstract excerpt

<h4>ABSTRACT</h4> Congenital Zika syndrome (CZS), the set of fetal and neonatal complications associated with Zika virus (ZIKV) infection in pregnancy, was first noted during the outbreak in the Americas in 2015-16. However, there was an unequal distribution of ZIKV cases and severe outcomes in all areas where ZIKV emerged in the Americas, demonstrating that the risk of CZS varied over space and time. Recently, w...

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Literature Corpus work
64c28c1f-2d24-5c9d-871f-6be2724199e1
DOI
10.1101/2025.02.12.637947
Open publication

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Zika virus-induced fetal demise is driven by strain- and dose-specific RLR-driven activation of the interferon response in the decidua, placenta, and fetus in <i> Ifnar1 <sup>-/-</sup> </i> miceDOI 10.1101/2025.02.12.637947
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