Article

Epigenetic Element-Based Transcriptome-Wide Association Study Identifies Novel Genes for Bipolar Disorder

2020-07-24

Abstract excerpt

Bipolar disorder (BD) is a highly heritable neuropsychiatric disorder characterized by recurrent episodes of depression and mania. Since the signals identified by genome-wide association study (GWAS) often reside in the non-coding regions, understanding the biological relevance of these genetic loci has proven to be complicated. Transcriptome-wide association studies (TWAS) providing a powerful approach to identif...

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Literature Corpus work: 64bb59f9-919a-52bc-9ebf-100433b14aa5
DOI: 10.1101/2020.07.23.20161174

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