Article
Phenotypes, mechanisms and therapeutics: insights from bipolar disorder GWAS findings.
Molecular psychiatry - 1 Jul 2022
Li Ming, Li Tao, Xiao Xiao, Chen Jun, Hu Zhonghua, Fang Yiru
Abstract excerpt
Genome-wide association studies (GWAS) have reported substantial genomic loci significantly associated with clinical risk of bipolar disorder (BD), and studies combining techniques of genetics, neuroscience, neuroimaging, and pharmacology are believed to help tackle clinical problems (e.g., identifying novel therapeutic targets). However, translating findings of psychiatric genetics into biological mechanisms...
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