Article
Systematic genetic analyses of genome-wide association study data reveal an association between the key nucleosome remodeling and deacetylase complex and bipolar disorder development.
Bipolar disorders - 1 Jun 2018
Xiang Bo, Liu Kezhi, Yu Minglan, Liang Xuemei, Zhang Jin, Lei Wei, Huang Chaohua, Chen Jing, Gu Xiaochu, Li Nian, Wu Guoying, Wang Yan, He Wenying, Tan Jinhua, Zhang Tao
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWASs) are used to identify genetic variants for association with bipolar disorder (BD) risk; however, each GWAS can only reveal a small fraction of this association. This study systematically analyzed multiple GWAS data sets to provide further insights into potential causal BD processes by integrating the results of Psychiatric Genomics Consortium Phase I (PGC-I) for...
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