Article

Diabetes mellitus is associated with a shared hyper-inflammatory immune response in melioidosis and tuberculosis patients: an observational case-control study

2024-06-01

Abstract excerpt

<h4>Background: </h4> Melioidosis is a serious infection caused by the bacterium Burkholderia pseudomallei with a case fatality rate of up to 40% in Northeast Thailand. Diabetes increases the risk of developing melioidosis by 12-fold. A similar, but less marked, relationship with diabetes is seen in tuberculosis (TB) patients, with a 3-fold increased risk of developing TB in people with diabetes. However, the mech...

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Literature Corpus work: edb1a481-85dc-5b64-bd17-effd9fee5ca2
DOI: 10.1101/2024.05.31.24308267

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