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Article

Fitness of artemisinin-resistant Plasmodium falciparum in vitro.

The Journal of antimicrobial chemotherapy - 1 Oct 2015

Hott Amanda, Tucker Matthew S, Casandra Debora, Sparks Kansas, Kyle Dennis E

Abstract excerpt

OBJECTIVES: Drug resistance confers a fitness advantage to parasites exposed to frequent drug pressure, yet these mutations also may incur a fitness cost. We assessed fitness advantages and costs of artemisinin resistance in Plasmodium falciparum in vitro to understand how drug resistance will spread and evolve in a competitive environment. METHODS: Genotyping of SNPs, drug susceptibility assays and copy number...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26203183
DOI: 10.1093/jac/dkv199
PMCID: PMC4668880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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