Article

Cell cycle oscillations in a polarity network facilitate state switching by morphogenetic cues

2025-10-13

Abstract excerpt

The proper establishment of cell form, fate, and function during morphogenesis requires precise coordination between cell polarity and developmental cues. To achieve this, cells must establish polarity domains that are stable yet sensitive to guiding cues. Here we show that C. elegans germline blastomeres resolve this trade-off by creating a time-varying polarization landscape. Specifically, coupling the PAR pola...

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Literature Corpus work: 64196bed-90b0-5a1f-8d31-d0a277aa8c9d
DOI: 10.1101/2025.10.12.681824

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