Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases.

doi:10.1242/dev.00284

Article

Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases.

Development (Cambridge, England) - 1 Apr 2003

Cuenca Adrian A, Schetter Aaron, Aceto Donato, Kemphues Kenneth, Seydoux Geraldine

Abstract excerpt

Polarization of the C. elegans zygote along the anterior-posterior axis depends on cortically enriched (PAR) and cytoplasmic (MEX-5/6) proteins, which function together to localize determinants (e.g. PIE-1) in response to a polarizing cue associated with the sperm asters. Using time-lapse microscopy and GFP fusions, we have analyzed the localization dynamics of PAR-2, PAR-6, MEX-5, MEX-6 and PIE-1 in wild-type...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases.

Abstract excerpt

Topics

Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases.

Abstract excerpt

Topics

Related research