Transethnic, Genome-Wide Analysis Reveals Immune-Related Risk Alleles and Phenotypic Correlates in Pediatric Steroid-Sensitive Nephrotic Syndrome.

doi:10.1681/ASN.2017111185

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Article

Transethnic, Genome-Wide Analysis Reveals Immune-Related Risk Alleles and Phenotypic Correlates in Pediatric Steroid-Sensitive Nephrotic Syndrome.

Journal of the American Society of Nephrology : JASN - 1 Jul 2018

Debiec Hanna, Dossier Claire, Letouzé Eric, Gillies Christopher E, Vivarelli Marina, Putler Rosemary K, Ars Elisabet, Jacqz-Aigrain Evelyne, Elie Valery, Colucci Manuela, Debette Stéphanie, Amouyel Philippe, Elalaoui Siham C, Sefiani Abdelaziz, Dubois Valérie, Simon Tabassome, Kretzler Matthias, Ballarin Jose, Emma Francesco, Sampson Matthew G, Deschênes Georges, Ronco Pierre

Abstract excerpt

Background Steroid-sensitive nephrotic syndrome (SSNS) is a childhood disease with unclear pathophysiology and genetic architecture. We investigated the genomic basis of SSNS in children recruited in Europe and the biopsy-based North American NEPTUNE cohort.Methods We performed three ancestry-matched, genome-wide association studies (GWAS) in 273 children with NS (Children Cohort Nephrosis and Virus [NEPHROVIR]...

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PMID: 29903748
DOI: 10.1681/ASN.2017111185
PMCID: PMC6050942

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BTNL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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