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Article

Hepatic serine and lipid metabolism drive diabetic peripheral neuropathy

2022-01-14

Abstract excerpt

<title>Abstract</title> <p>Type 2 diabetes represents a disease spectrum in which chronic metabolic dysfunction damages multiple organ systems including liver, kidneys, and peripheral nerves1,2. While onset and progression of these co-morbidities are linked with insulin resistance, hyperglycaemia and dyslipidemia3-7, aberrant amino acid metabolism also contributes to pathogenesis of diabetes and potentially its c...

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Literature Corpus work
63846d41-769d-552b-a796-de63b44dd59b
DOI
10.21203/rs.3.rs-1189916/v1
Open publication

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Hepatic serine and lipid metabolism drive diabetic peripheral neuropathyDOI 10.21203/rs.3.rs-1189916/v1
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