Article
Amino Acid Metabolism in Lupus.
Frontiers in immunology - 1 Jan 2021
Kono Michihito, Yoshida Nobuya, Tsokos George C
Abstract excerpt
T cell metabolism is central to cell proliferation, survival, differentiation, and aberrations have been linked to the pathophysiology of systemic autoimmune diseases. Besides glycolysis and fatty acid oxidation/synthesis, amino acid metabolism is also crucial in T cell metabolism. It appears that each T cell subset favors a unique metabolic process and that metabolic reprogramming changes cell fate. Here, we...
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