Article
Aberrant DEGS1 sphingolipid metabolism impairs central and peripheral nervous system function in humans
2018-06-19
Abstract excerpt
Sphingolipids including ceramides are important components of cellular membranes and functionally associated with fundamental processes such as cell differentiation, neuronal signaling and myelin sheath formation. Defects in the synthesis or degradation of sphingolipids are associated with various neurological pathologies, however, the entire spectrum of disorders affecting sphingolipid metabolism remains elusive....
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 8dd0f5fd-18b5-503b-a621-c0ed9194684c
- DOI
- 10.1101/347591