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A drug cocktail of rapamycin, acarbose, and phenylbutyrate enhances resilience to features of early-stage Alzheimer’s disease in aging mice

2024-01-30

Abstract excerpt

The process of aging is defined by the breakdown of critical maintenance pathways leading to an accumulation of damage and its associated phenotypes. Aging affects many systems and is considered the greatest risk factor for a number of diseases. Therefore, interventions aimed at establishing resilience to aging should delay or prevent the onset of age-related diseases. Recent studies have shown a three-drug cockta...

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Literature Corpus work
636c4eb6-e868-52b9-a79a-9246a9873ddf
DOI
10.1101/2024.01.26.577437
Open publication

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A drug cocktail of rapamycin, acarbose, and phenylbutyrate enhances resilience to features of early-stage Alzheimer’s disease in aging miceDOI 10.1101/2024.01.26.577437
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