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Article

Mouse Models to Disentangle the Hallmarks of Human Aging

13 Sept 2018

Abstract excerpt

Model organisms have provided fundamental evidence that aging can be delayed and longevity extended. These findings gave rise to a new era in aging research aimed at elucidating the pathways and networks controlling this complex biological process. The identification of 9 hallmarks of aging has established a framework to evaluate the relative contribution of each hallmark and the interconnections among them. In...

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PMID: 30355076
DOI: 10.1161/circresaha.118.312204

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